Clinical analysis of kasabach-merritt syndrome in 17 neonates

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Clinical analysis of kasabach-merritt syndrome in 17 neonates

BACKGROUND Kasabach-Merritt syndrome (KMS) is characterized by giant hemangiomas and severe thrombocytopenia, which may result in life-threatening multi-organ hemorrhage. This study evaluated the clinical characteristics, treatments, and outcomes in neonates with KMS, in order to find out the optimal therapy. METHODS The clinical data of 17 patients treated for KMS in the Department of Neonat...

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Kasabach-Merritt syndrome.

Hemangiomas of infancy are usually congenital lesions. Occasionally they are associated with microangiopatbic bemolytic anaemia, thrombocytopenia, and a consumptive coagulopathy. This is most often associated with cavernous hemangiomas. Thrombocytopenia associated with giant cavernous hemangiomas was first noted by Kasabach and Merritt in 1940. As the primary mechanism of platelet destruction i...

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About the Treatment of Kasabach-Merritt Syndrome

94 To the Editor, Dr. Emre and colleagues briefly reported on a 24-year-old female with Kasabach-Merritt syndrome in the most recent issue of this journal [1]. Three units of fresh frozen plasma were administrated within 3 days to the patient for the correction of severe hypofibrinogenemia despite a very high D-dimer level (5000 ng/mL), both of which reflected consumption coagulopathy, as state...

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[A case report of Kasabach-Merritt syndrome].

Kasabach Merritt syndrome (KMS) is an uncommon complication of large haemangioma in which there is thrombocytopenia and coagulopathy. We report a case of a new born male baby presented with a large haemangioma on the right upper extremity and his initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed as a case of KMS and treated with oral prednisolone. 1. Assoc...

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Metastatic Angiosarcoma and Kasabach-Merritt Syndrome

Angiosarcomas are exceedingly rare tumors that are often difficult to diagnose. Exceptionally unusual is the presentation of these tumors with Kasabach-Merritt Syndrome, a curious form of intratumoral coagulation that can be impossible to distinguish from intravascular coagulation, which is more common. Instant recognition of this clinical association can help making a prompt diagnosis and time...

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ژورنال

عنوان ژورنال: BMC Pediatrics

سال: 2014

ISSN: 1471-2431

DOI: 10.1186/1471-2431-14-146